Fluorometers are used for precise quantitation of biological molecules including nucleic acids and proteins in microliter (μl) samples.
Rapid Eight Channel UV-Vis
Based on the award-winning technology of the DS-11 Series, DS-8X Eight Channel Spectrophotometers ensure confidence in every measurement.
DS-8X
Eight Channel Spectrophotometer
Why Choose the DS-8X?
DeNovix takes high throughput spectrophotometry to a new level of performance with the DS-8X Eight Channel Spectrophotometer. This easy-to-use, stand-alone device delivers full spectrum UV-Vis analysis, making it ideal for rapid nucleic acid and protein quantification.
Rapid Multichannel UV-Vis
Analyze 8 samples in as little as 10 seconds, or a single sample in 2 seconds.
GxP Compliance Ready
Optional 21 CFR Part 11 Software, IQ-OQ available. Flexible export in LIMS-compatible formats.
Eliminate Measurement Errors
Designed for sensitivity and accuracy, SmartPath™ technology algorithms provide real-time optimization of every sample.
Proven DeNovix Technology
Based on innovations that make DeNovix instruments trusted by scientists, the DS-8X ensures confidence in every measurement.
Maintenance-Free Design
Lifetime consistency; no recalibration required for the life of the instrument.
Powerful EasyApps™ Software
Easy-to-use, intuitive software designed by life scientists, for life scientists.
The DeNovix Difference: SmartQC™ Sample Assurance
The DS-8X employs a suite of quality assurance features to ensure reliable and accurate microvolume measurements. Proprietary DeNovix SmartPath™ technology uses micron-level pathlength control and immediate absorbance feedback. The measurement pathlength for every sample is automatically optimized through continuous sample compression.
Bridge Testing™ verification eliminates unreliable results that stem from broken sample columns or loading issues. The algorithm detects unbridged samples and adjusts in real-time to deliver accurate results, even for challenging 1 µL protein samples.
Automatically Optimized for Every Sample
Multiple algorithms ensure confidence in results while also providing important information about possible sample anomalies.
GxP Compliance Ready
Optional 21 CFR Part 11 Software
EasyApps Secure provides an optional suite of software controls that allow regulated GxP facilities to easily add DS-8X instruments to their compliant workflows (view the compliance statement). The software is fully integrated within the onboard operating system and includes a range of features essential to ensuring compliance, including:
- Password protected system access
- Integrated electronic signature controls
- Comprehensive user account management
- Secure audit trail recording
- Advanced data handling and export tools
Designed by Life Scientists, For Life Scientists
Multi-Mode Flexibility
- Full spectrum UV-Vis: 190 – 840 nm
- Single Sample (2 sec); Up to Eight Samples (~10 sec)
- 1µL UV-Vis, Cuvette, and Fluorescence options
User-Friendly Pipette Guide
Our ergonomic pipette guide ensures error-free sample loading. Adjustable to accommodate for left- or right-handed users and any size pipette tip. Each instrument ships with a pipette guide on both sides.
Stand-Alone (No PC)
Easy operation and no additional laptop or PC maintenance thanks to a 7 inch HD touchscreen, compatible with all common laboratory gloves.
LED Sample Tracker
Never lose track of where you are on your plate! This plug and play USB accessory links with the DS-8X to help guide your loading process. Software-controlled LEDs illuminate the correct sample column to measure based on your plate layout.
Software Features
Setup
Easily configure your plate setup to define sample IDs, blanks or empty wells.
- Option to import a pre-configured .csv file with your template
- Easily create, save, or edit plate templates or import from LIMS
- Experiment ID groups data for each plate for easy reference and data retrieval
Results
The DS-8X is equipped with pre-configured applications for each of the most commonly measured biomolecule types. All apps readily present results onscreen in as little as 10 seconds for eight sample mode, and 2 seconds for single sample mode.
- Concentration
- Purity Ratios / SmartQC Contamination Alerts
- Spectra Graphs
EasyApps™ Software
EasyApps software is designed by life scientists and combines with an intuitive touchscreen interface to ensure error-free operation. Every instrument is ready to go right out of the box – no PC set-up or software installation required.
Improve Workflow Efficiency
AutoRun makes quantification as easy as lifting, loading, and lowering. When AutoRun is turned on, simply lift the instrument arm and load your sample. The software will automatically initiate a measurement when the arm is closed. Sample tracking automatically progresses to the next sample column.
User Accounts & Data Handling
- Password-protected user accounts available
- All data is automatically saved and searchable in the Data App
- Easy to search, sort, and analyze archived data
Exporting & Connectivity
- Wi-Fi, Ethernet & USB connectivity
- Flexible export in LIMS-compatible formats
- Export via email, network & label printers, USB, and network drives
- Print microfuge tube labels using a DeNovix supported printer
- Print reports to a networked printer or DeNovix supported label printer
SmartQC™ Contamination Alerts
During measurements, SmartQC will check samples against well-established purity ratios. Samples that do not meet purity specifications will be flagged with visual alert icons. Tapping on an alert icon on the Run screen will provide detailed information regarding the possible reasons for the high or low value.
DS-Series Models and Specifications
Which DS-Series model is right for your lab? Compare all spectrophotometer fluorometer models with the full list of features and specifications.
 DS-11 Series |  DS-8X |  DS-7 |  DS-C |  QFX |
|
|---|---|---|---|---|---|
| 1 µL UV-Vis Samples | ✅ | ✅ x 8 | ✅ | - | - |
| Cuvette Absorbance | ✅ | ✅ | ✅ | ✅ | - |
| Fluorescence | ✅ | Add On | - | Add On | ✅ |
| Detection Limit (dsDNA) | 0.0005 – 37,500 ng/µL | 2 – 11,000 ng/µL | 2 – 15,000 ng/µL | 0.04 – 75 ng/µL | 0.0005 – 4,000 ng/µL |
A Splash of Color in Your Lab
The DS-8X is available in four colors: Brazilian Blue, Arctic White, Tungsten Silver, and Fire Red.
Wide Range of Applications
The DS-8X excels in a wide range of applications through the ease of use, wide dynamic range, and contamination detection of UV-Vis. The DS-8X is also compatible with the FX Fluorescence Module to enable the enhanced sensitivity and specificity of fluorescence quantification.
Nucleic Acid Quantification
- Measurement ranges
- 2 – 11,000 ng/µL (dsDNA)
- 1.6 – 8,800 ng/µL (RNA)
- Separate pre-configured apps for optimized workflow
- Sample contaminant alerts
- Pre-configured and user-defined factors for ssDNA ensures appropriate concentration calculations
- 260/280 and 260/230 ratios displayed
- 11 pre-configured dyes and fluorophores for Microarray
- Option to add an unlimited number of new dyes for quick recall in Microarray
Protein Quantification
- Measurement range
- 0.1 – 330 mg/mL (BSA)
- 0.6 – 161 mg/mL (IgG)
- Pre-configured and user-defined protein types for A280 and Labeled Proteins
- Pre-configured Peptide app for easy peptide analysis at A205/215
- Quick addition of new user defined protein types for improved workflow
- 11 pre-configured dyes and fluorophores for Labeled Proteins
- Option to add an unlimited number of new dyes for quick recall in Labeled Proteins
- BCA, Bradford, Lowry and 660 nm colorimetric assays optimized for ease of use
- Quick save and recall of standard curves available
Fluorescence Quantification
- Measurement ranges
-
*0.0005 ng/µL – 4000 ng/µL dsDNA
-
*0.25 – 1500 ng/µL RNA
-
- Four user-selectable LED light sources – compatible with all commonly used quantification assays e.g. DeNovix assays, Thermo Fisher Qubit™ assays, Thermo Fisher Quant-iT™ assays, and Promega Quantifluor™ assays
- Easy configuration of additional assays
- Single or multi-replicate standard curve options
- User control of line fit, trend line analysis, subtraction of blank
- User control of assay and reported sample concentration units
- Save and re-use curves and lists of standard concentrations
*Using DeNovix Fluorescence Quantification assays. For other kits please see manufacturer’s specifications.
Custom Fluorescence Apps
- Add new standard curve based fluorescent assays (nucleic assay, protein or other)
- Basic Fluorometer app returns RFU values for a wide range of fluorophores
Upgrade to fluorescence with the FX Module, and instantly access DeNovix fluorometer EasyApps
UV-Vis and Custom Apps
- Simple but powerful apps enable measurement of more than just nucleic acids and proteins
- Full spectrum analysis (190 – 840 nm)
- Broad absorbance range for highly concentrated samples (up to 750 A, 1 cm equivalent)
- Add new user-defined standard curve methods
- Add custom formulas to eliminate downstream calculations
- Add kinetics methods (DS-8X+)
Kinetics and OD600
- DS-8X+ model enables cuvette-based kinetics studies
- Full spectrum analysis (190 – 840 nm), with dual or single wavelength monitoring
- Built-in heater with temperature control between 37° and 45° C.
- Dual graphs enable absorbance vs. time or absorbance vs. wavelength plots
- All kinetic data automatically saved to large on-board memory
- Estimated cell number calculator included in OD 600 app
Additional Options for Extended Flexibility
Sample Tracker
The Sample Tracker USB accessory uses software-controlled LEDs to illuminate the correct sample column to measure on your plate.
FX Fluorometer Module
USB plug and play accessory to immediately enable DeNovix fluorometer EasyApps.
Cuvette Mode
Extend the lower detection limit with the built in cuvette option (DS-8X+).
Resources
User Guide for the DS-11 Series Spectrophotometer / Fluorometer.
Whether you're curious about optimizing sample prep or LED selection, check out this resource on the best practices for fluorescence measurement.
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